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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-506-3p
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB cell lines WERI-RB1, HXORb44, Y79 and SO-RB50; human RPE cell line ARPE-19; RB samples and adjacent noncancerous tissues
Methods transfection, qPCR, MTT assay, colony formation assay, apoptosis assay, luciferase reporter assay, Western blot
Expression pattern down-regulated
Functional description miR-506-3p functions as a potential tumor suppressor in RB by directly targeting NEK6.
PubMed ID 30080301
Year 2018
Title MiR-506-3p inhibits cell proliferation, induces cell cycle arrest and apoptosis in retinoblastoma by directly targeting NEK6.
Drug-related ncRNA NO

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