ncRNA name | hsa-miR-506-3p |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB cell lines WERI-RB1, HXORb44, Y79 and SO-RB50; human RPE cell line ARPE-19; RB samples and adjacent noncancerous tissues |
Methods | transfection, qPCR, MTT assay, colony formation assay, apoptosis assay, luciferase reporter assay, Western blot |
Expression pattern | down-regulated |
Functional description | miR-506-3p functions as a potential tumor suppressor in RB by directly targeting NEK6. |
PubMed ID | 30080301 |
Year | 2018 |
Title | MiR-506-3p inhibits cell proliferation, induces cell cycle arrest and apoptosis in retinoblastoma by directly targeting NEK6. |
Drug-related ncRNA | NO |
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